Polynucleotides (Ameela)

Discover the next generation of skin rejuvenation with Ameela Polynucleotides at McKeown Medical. This regenerative treatment works at a cellular level to restore hydration, structure and radiance from within — for smoother, healthier, naturally luminous skin. Performed exclusively by aesthetic expert Dr Sharon Ritchie for beautifully refined results.

At a glance

Every patient is unique, and during our consultation process, we work with you to develop a bespoke treatment plan based on what you want to achieve.

Duration

15-30 minutes

Anaesthetic

Topical

Downtime

Minimal

Length of results

Maintenance at 6-9 months

Pricing

£325 per session, £600 for 2 sessions

How Does It Work?

Regenerative skin rejuvenation using your body’s natural repair pathways

Polynucleotides are one of the most exciting developments in regenerative aesthetics — and at McKeown Medical, we are proud to offer treatment using Ameela, a premium, medical-grade polynucleotide product designed to stimulate deep, cellular renewal.

Rather than adding volume like dermal fillers, polynucleotides work at a biological level to improve skin quality, helping to restore hydration, structure and luminosity from within. The result is healthier, smoother and more resilient skin, with a natural radiance that cannot be achieved through traditional injectables alone.

All treatments are performed by Dr Sharon Ritchie, our aesthetic doctor with an expert focus on advanced injectables and skin booster treatments. Dr Sharon has a particular passion for regenerative approaches that enhance skin quality — making her ideally suited to deliver Ameela for refined, elegant results.

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What are polynucleotides?

Polynucleotides are highly purified fragments of DNA derived from natural, safe biological sources. When injected into the skin, they:

stimulate fibroblasts to trigger collagen and elastin production
improve cellular metabolism and tissue regeneration
enhance hydration by increasing extracellular matrix activity
reduce inflammation and oxidative stress within the skin

Unlike hyaluronic acid fillers, which add immediate volume, polynucleotides restore function, helping the skin behave as it did when it was younger.

Think of them as a reset button for tired, ageing or dehydrated skin.

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Why we use Ameela

Ameela is an advanced, medical-grade polynucleotide product renowned for its high purity and regenerative performance. It has been established as the most premium brand of polynucleotides currently available. It is particularly effective in delicate areas where other injectables can be difficult to use — such as the under-eyes — and is one of the few treatments that can genuinely improve crepey texture, fine lines and chronic dehydration.

Benefits of Ameela include:

noticeable improvement in skin quality and firmness
reduction in under-eye hollowing, fine lines and pigmentation
increased elasticity and natural radiance
more even tone and reduction in dullness
long-lasting bio-stimulatory effect

Ameela is not a filler — it refines, smooths and renews.

What areas can polynucleotides treat?

Ameela polynucleotides can be used on multiple areas, including:

Under-eye hollows and crepey texture
Face (global skin quality improvement)
Neck and décolleté
Hands
Acne-scarred or compromised skin
Areas affected by sun damage or chronic dehydration

This makes it a powerful option for patients who want better-quality skin but aren’t ready for filler, laser or radiofrequency.

Are you ready to start your consultation?

If you would like to explore whether Ameela polynucleotides are right for you, book a consultation with Dr Sharon Ritchie.

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Am I A Good Candidate?

Polynucleotide treatment is ideal if you:

want to improve skin quality rather than add volume
have crepiness, dehydration or early signs of ageing
have dark circles or under-eye hollows where filler is not suitable
prefer a regenerative, subtle and natural approach

It is also an excellent option for those who have previously had filler and now want to focus on skin health and longevity.

Pricing

Your treatment plan will be tailored to your individual needs and the results you are looking to achieve.

Discover our full price list

Polynucleotides (Ameela)

Per session £325

Two sessions £600

Per session

Two sessions

Polynucleotides (Ameela)

£325

£600

What to Expect

The treatment process

Consultation with Dr Sharon Ritchie to assess your concerns and determine suitability.
Topical anaesthetic is applied for comfort.
Micro-injections of Ameela are placed strategically into the skin.
You can return to normal activities immediately, with only mild redness or swelling expected.

A typical treatment course is:

Two sessions spaced four weeks apart, with one maintenance treatment every 6–9 months depending on your skin.

Results

You may notice improved hydration and radiance within the first week, but the most significant changes occur gradually over several weeks as cellular regeneration takes place.

Results include:

smoother texture
brighter, more even skin tone
reduced fine lines and crepiness
tighter, more resilient skin

Polynucleotides continue to stimulate regeneration long after the injections — meaning results are progressive and naturally long-lasting.

Why choose McKeown Medical?

Treatments are performed exclusively by Dr Sharon Ritchie, aesthetic doctor with advanced training in injectables and a special interest in skin boosters and regenerative treatments.
We use Ameela, a premium, medical-grade polynucleotide product that delivers reliable, visible results.
Your treatment plan is personalised — focusing on natural enhancement, not over-correction.
All procedures take place in our doctor-led clinic with comprehensive follow-up and support.

Common Questions

What are polynucleotides?

Polynucleotides are highly purified DNA fragments that stimulate deep regeneration within the skin. Unlike fillers, which add volume, polynucleotides improve the quality, hydration and resilience of the skin by activating fibroblasts and boosting collagen and elastin production.

How is Ameela different from traditional dermal fillers?

Ameela does not add volume or change facial structure. Instead, it improves the health of the skin from within — smoothing, hydrating and rejuvenating tissue over time. Results are subtle, natural and focused on quality, not augmentation.

What concerns can Ameela treat?

Ameela is especially effective for delicate or difficult areas, including:

Under-eye hollows and crepey texture
Fine lines and early laxity
Dehydrated, dull or sun-damaged skin
Neck, décolletage and hands

How many treatments will I need?

Most patients need a course of two sessions spaced about four weeks apart, followed by maintenance every 6–9 months depending on skin needs.

When will I see results?

Some patients notice increased hydration and brightness within the first week, but the most significant changes occur gradually over several weeks as cellular regeneration takes place.

Is there any downtime?

Downtime is minimal. You may experience small bumps, light redness or swelling at the injection points that typically settle within a few hours to 48 hours. Makeup can usually be worn the following day.

Your Expert Team

Aesthetic Doctor

Dr Sharon Ritchie

Dr Sharon Ritchie has been a qualified doctor for over 30 years, and 10 of those years have been spent practicing aesthetic medicine. Sharon trained as a GP and practiced between general practice and aesthetic medicine, before joining McKeown Medical to pursue her passion of aesthetic medicine on a full time basis.

Meet Dr Sharon Ritchie